• info@vivavel.com
  • +919818262686
  • +919818262686

Medical Treatments

Gastrointestinal Stromal Tumor (GIST)

Gastrointestinal Stromal Tumor (GIST) is a type of cancer originating in the digestive tract, typically in the stomach or small intestine. While rare, GIST is the most common type of tumor within the digestive tract's connective tissues. The cancer arises from cells in the gastrointestinal tract wall called the interstitial cells of Cajal (ICC), which help control muscle contractions in the gut.

Signs & Symptoms

The symptoms of GIST can vary depending on its size, location, and stage. Early stages may not cause noticeable symptoms, but as the tumor grows, signs may include:

  • Abdominal pain or discomfort – Constant or intermittent pain in the stomach.
  • Nausea and vomiting – Unexplained nausea and vomiting, often after meals.
  • Unintentional weight loss – Losing weight without trying.
  • Bowel obstruction – A larger tumor might block the digestive tract, causing pain and bloating.
  • Blood in stools or vomit – Sometimes seen as black, tarry stools or red vomit.
  • Fatigue – Often related to blood loss or anemia.
Causes

GIST primarily results from genetic mutations, often spontaneous rather than inherited. Researchers have found links to mutations in two genes, KIT and PDGFRA. These mutations cause cells to grow and divide uncontrollably, leading to tumors. While some genetic syndromes are linked to GIST, most cases are not inherited.

When to seek medical attention?

Seek medical attention if you experience persistent abdominal pain, unexplained weight loss, nausea, or blood in stools. Early diagnosis improves the chances of effective treatment, so consult a healthcare provider if you notice any concerning symptoms.

Diagnostics & Tests

Several diagnostic tests and procedures help confirm GIST:

  • Endoscopy – A camera on a flexible tube is inserted through the mouth to inspect the digestive tract.
  • Imaging scans (CT, MRI, PET scans) – Used to locate and measure the tumor.
  • Biopsy – Tissue samples are taken and analyzed to determine the type and aggressiveness of the tumor.
  • Molecular testing – Determines if KIT or PDGFRA mutations are present, which can guide treatment plans.
Do’s & Don’ts

Do's

  • Adhere to medication schedules and follow the doctor's recommendations.
  • Attend all follow-up appointments to monitor for recurrence or side effects.
  • Stay informed about your condition and ask your healthcare team questions.
  • Maintain a balanced diet rich in nutrients and consult a dietitian for personalized advice.

​​​​​​​ Don'ts

  • Don't skip medication or alter dosages without consulting your doctor.
  • Avoid processed foods and excessive sugars, as these may impact treatment efficacy.
  • Do not ignore new symptoms – immediately report any changes to your healthcare provider.
  • Avoid self-medicating – Always consult a healthcare provider before taking new medications or supplements.

Disclaimer:

Our medical content authors have diligently gathered and synthesized information on this topic to offer valuable insights to our readers. Drawing from a range of reputable medical journals and health resources, this content aims to enhance understanding of the subject. It's important to remember that while this information is informative, it should not replace personalized consultation or treatment from a qualified physician. For further details, please refer to our Editorial Policy.

For this topic, our authors used some of the following resources:

  1. https://my.clevelandclinic.org/health/diseases/15254-abdominal-adhesions
  2. https://surgery.ucsf.edu/condition/abdominal-adhesions
  3. https://drruscio.com/abdominal-adhesions/
  4. https://www.bupa.co.uk/health-information/digestive-gut-health/adhesions
  5. https://www.healthline.com/health/adhesiolysis

Frequently Asked Questions For Gastrointestinal Stromal Tumor (GIST)

Early-stage GIST can often be treated effectively with surgery. Advanced or metastatic GIST can be managed with targeted therapies, but a complete cure is more challenging.

A healthy lifestyle, balanced diet, and regular follow-up care can support overall health and improve quality of life but cannot replace medical treatment.

Imatinib blocks proteins made by KIT or PDGFRA gene mutations, often slowing or stopping tumor growth.

Most GISTs are not hereditary, though genetic syndromes can sometimes play a role.

Survival rates depend on the tumor's stage, location, and response to treatment. With targeted therapies, many patients live longer than previously possible.

Best Hospitals in Gastrointestinal Stromal Tumor (GIST)

Explore All Hospitals in Gastrointestinal Stromal Tumor (GIST)
Max Super Speciality Hospital, Saket, New Delhi – JCI-accredited multispecialty hospital offering world-class healthcare with cutting-edge infrastructure.
Max Super Speciality Hospital, Saket

Press Enclave Road, Saket, New Delhi

BLK-MAX Super Specialty Hospital, Delhi – State-of-the-art medical facility
BLK-MAX Super Specialty Hospital

Pusa Road, Radha Soami Satsang, Rajendra Place New Delhi, 110005 India

Accord Superspeciality Hospital, a leading healthcare facility in Faridabad, offering advanced treatments with modern infrastructure.
Accord Superspeciality Hospital

Budena Village, Sector 86, Faridabad, Haryana 121002, India

High-tech medical equipment at Artemis Hospital, Gurgaon, ensuring accurate diagnostics and advanced treatment solutions.
Artemis Hospital

Artemis Hospitals Sector 51, Gurugram 122001 Haryana, India

SHALBY Sanar International Hospital, Gurugram – trusted healthcare destination for global patients via VivaVel.com
SHALBY Sanar International Hospitals, Gurugram

Golf Course Rd, Parsvnath Exotica, DLF Phase 5, Sector 53, Gurugram, Haryana Gurgaon, 122022 India

PARAS Health, Gurugram – top multispecialty hospital for international patients via VivaVel.com
PARAS Health, Gurugram

C-1, Sushant Lok- 1, Sector-43, Phase- I, Gurugram, Haryana, 122002

Top Doctors in Gastrointestinal Stromal Tumor (GIST)

Explore All Doctors in Gastrointestinal Stromal Tumor (GIST)
Ram Chandra Soni
  • Dr. Ram Chandra Soni
  • Chairman
  • Gastroenterology & Hepatology
  • 22 Years Experience
  • Accord Superspeciality Hospital

Dr. Ram Chandra Soni is one of the leading Gastroenterologists in Faridabad, India. He has vast experience in Advanced Interventional Endoscopy and Gastroenterology. ...

View Details Book Consultation
Pradeepta K Sethy
  • Dr. Pradeepta K Sethy
  • Director Of Gastroenterology Department,...
  • Medical Gastroenterologist
  • 23 Years Experience
  • Manipal Hospital (E.M. Bypass), Kolkata

Dr. Pradeepta Kumar Sethy is a highly experienced gastroenterologist with over 23 years in the field, currently serving as the Director of the Gastroenterology Department at ...

View Details Book Consultation
Nidhi Rawal
  • Dr. Nidhi Rawal
  • Consultant
  • Pediatric Gastroenterologist
  • 13 Years Experience
  • Madhukar Rainbow Children's Hospital

Dr. Nidhi Rawal is a highly regarded Pediatric Gastroenterologist and Hepatologist based in New Delhi. She has 11 years of experience in her field. She specia...

View Details Book Consultation
Vivek Vij
  • Dr. Vivek Vij
  • Chairman
  • Gastroenterology And Hepatobiliary Scien...
  • 15 Years Experience
  • Fortis Escorts Heart Institute

Dr. Vivek Vij is an accomplished liver transplant surgeon credited with developing living donor surgery and implementing safety protocols to achieve a 100% donor safety profi...

View Details Book Consultation
Subrat Kumar Acharya
  • Dr. Subrat Kumar Acharya
  • Executive Director, Gastroenterology
  • Gastroenterology And Hepatobiliary Scien...
  • 42 Years Experience
  • Fortis Escorts Heart Institute

Dr. Subrat Kumar Acharya is the Executive Director of Gastroenterology & Hepatobiliary Sciences at Fortis Escorts, Okhla Road, New Delhi. He is a renowned Gastroe...

View Details Book Consultation
Pankaj Puri
  • Dr. Pankaj Puri
  • Director Gastroenterology
  • Gastroenterology And Hepatology
  • 33 Years Experience
  • Fortis Escorts Heart Institute

Dr (Brig) Pankaj Puri is the Director of Gastroenterology and Hepatology at the Fortis Escorts Liver and Digestive Diseases Institute, Okhla, New Delhi. He completed ...

View Details Book Consultation
X

Get FREE Evalution

Treatment Plan & Cost within 2 days

By submitting, you agree to our Terms & Conditions & Privacy Policy of VivaVel.com. captcha