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Tetralogy of Fallot (TOF)

Tetralogy of Fallot (TOF) is a congenital heart condition, meaning it develops before birth. It’s one of the most common heart defects in children, affecting blood flow from the heart to the rest of the body. TOF consists of four distinct heart abnormalities that can lead to insufficient oxygen in the blood, causing symptoms like cyanosis (bluish skin).

Signs & Symptoms

Children with TOF often display symptoms soon after birth, though they can vary in severity:

  • Cyanosis: Bluish skin color, especially noticeable on lips, nails, and face.
  • Heart Murmur: An unusual whooshing sound heard during a heartbeat.
  • Difficulty Breathing: Especially after physical activity.
  • Fatigue or Tiredness: Trouble keeping up with peers physically.
  • Clubbing of Fingers and Toes: Swelling and broadening of fingertips or toes.
  • Fainting or Dizziness: Due to reduced blood oxygen.
  • Poor Weight Gain: In babies, trouble feeding and gaining weight.
Causes

Some factors might increase the likelihood of Tetralogy of Fallot:

  • Genetic Factors: Family history of TOF or other congenital heart defects.
  • Chromosomal Abnormalities: Such as Down syndrome or DiGeorge syndrome.
  • Maternal Factors: Alcohol consumption, poor nutrition, or uncontrolled diabetes during pregnancy may increase risk.
When to seek medical attention?

If your child shows any symptoms of TOF, consult a pediatrician or cardiologist as soon as possible:

  • Cyanosis (blue-tinged skin, lips, nails).
  • Shortness of Breath or rapid breathing, especially during feeding or physical activity.
  • Clubbing of Fingers and Toes (enlarged fingertips due to low oxygen).
  • Poor weight gain and failure to thrive.
  • Heart Murmur (heard through a stethoscope).
  • Fatigue and Weakness.
  • "Tet Spells": Sudden episodes of cyanosis and breathlessness triggered by crying or exertion.
Diagnostics & Tests

A doctor may order the following tests to diagnose TOF and assess its severity:

  • Physical Examination: Detection of heart murmur and cyanosis.
  • Echocardiogram: Ultrasound imaging of the heart to visualize structural abnormalities.
  • Electrocardiogram (ECG): Detects right ventricular hypertrophy.
  • Chest X-ray: Shows an enlarged heart and reduced pulmonary blood flow.
  • Oxygen Saturation Test: Measures the oxygen level in the blood.
  • Cardiac Catheterization: Provides detailed images and measures pressures inside the heart.
Do’s & Don’ts

Do’s

  • Follow Up Regularly: Maintain appointments with the cardiologist for ongoing monitoring.
  • Medications as Prescribed: Medications may be required to manage symptoms and prevent complications.
  • Watch for Symptoms: Notice if cyanosis, fainting, or difficulty breathing increases, and seek medical advice.

Don’ts

  • Avoid High-Stress Activities: Particularly activities that cause excessive fatigue or oxygen depletion.
  • Limit High-Altitude Trips: Reduced oxygen levels at higher altitudes can exacerbate symptoms.
  • Delay Vaccinations: Avoid delaying any recommended vaccines, as infections can be more dangerous in children with TOF.

Disclaimer:

Our medical content authors have diligently gathered and synthesized information on this topic to offer valuable insights to our readers. Drawing from a range of reputable medical journals and health resources, this content aims to enhance understanding of the subject. It's important to remember that while this information is informative, it should not replace personalized consultation or treatment from a qualified physician. For further details, please refer to our Editorial Policy.

 

For this topic, our authors used some of the following resources:

  1. CDC - About Tetralogy of Fallot - Congenital Heart Defects
  2. Cleveland Clinic - Tetralogy of Fallot
  3. Americal Heart Association - What is Tetralogy of Fallot
  4. NIH - Tetralogy of Fallot (TOF)
  5. Mayo Clinic - Tetralogy of Fallot - Disease & Conditions 

 

Frequently Asked Questions For Tetralogy of Fallot (TOF)

While TOF is not “cured” per se, corrective surgery can help most children lead normal, active lives. Some may still need long-term follow-up for heart health.

Fetal echocardiography can detect TOF during pregnancy, typically around the 18th-22nd week of gestation.

Yes, some adults with TOF may have had incomplete repairs or require lifelong care.

Low-impact activities like walking and swimming are often safe, but discuss specific recommendations with a cardiologist.

Genetics may play a role, but TOF can occur even without family history. Genetic counseling may be recommended if you have a family history.

Best Hospitals in Tetralogy of Fallot (TOF)

Explore All Hospitals in Tetralogy of Fallot (TOF)
Max Super Speciality Hospital, Saket, New Delhi – JCI-accredited multispecialty hospital offering world-class healthcare with cutting-edge infrastructure.
Max Super Speciality Hospital, Saket

Press Enclave Road, Saket, New Delhi

Max Super Speciality Hospital, Vaishali – trusted hospital near Delhi for global patients via VivaVel.com
Max Super Speciality Hospital, Vaishali

Near Radisson Blu Hotel, Sector 1, Vaishali Ghaziabad, 201012 India

BLK-MAX Super Specialty Hospital, Delhi – State-of-the-art medical facility
BLK-MAX Super Specialty Hospital

Pusa Road, Radha Soami Satsang, Rajendra Place New Delhi, 110005 India

Accord Superspeciality Hospital, a leading healthcare facility in Faridabad, offering advanced treatments with modern infrastructure.
Accord Superspeciality Hospital

Budena Village, Sector 86, Faridabad, Haryana 121002, India

High-tech medical equipment at Artemis Hospital, Gurgaon, ensuring accurate diagnostics and advanced treatment solutions.
Artemis Hospital

Artemis Hospitals Sector 51, Gurugram 122001 Haryana, India

SHALBY Sanar International Hospital, Gurugram – trusted healthcare destination for global patients via VivaVel.com
SHALBY Sanar International Hospitals, Gurugram

Golf Course Rd, Parsvnath Exotica, DLF Phase 5, Sector 53, Gurugram, Haryana Gurgaon, 122022 India

Top Doctors in Tetralogy of Fallot (TOF)

Explore All Doctors in Tetralogy of Fallot (TOF)
Anil Saxena
  • Dr. Anil Saxena
  • Chairman Cardiology
  • Cardiologist
  • 35 Years Experience
  • Fortis Escorts Heart Institute

Dr. Anil Saxena is an Executive Director in the Department of Electrophysiology & Cardiac Pacing at Fortis Escorts Heart Institute. He is recognized for his exper...

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Kulbhushan Singh Dagar
  • Dr. Kulbhushan Singh Dagar
  • Principal Director, Chief Surgeon & Head...
  • Cardiologist
  • 30 Years Experience
  • Max Super Speciality Hospital, Saket

Dr. Kulbhushan S. Dagar is a highly experienced cardiac surgeon with over 21 years in the field. For the past 15 years, he has specialized in caring for infants and c...

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(Col) C.P. Roy
  • Dr. (Col) C.P. Roy
  • Visiting Consultant
  • Cardiologist
  • 38 Years Experience
  • Max Super Speciality Hospital, Saket

Dr. (Col.) C.P. Roy VSM is an accomplished heart specialist with over 30 years of experience in the Indian Armed Forces and leading medical institutions. He has held ...

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Ripen Gupta
  • Dr. Ripen Gupta
  • Principal Director & Unit Head - Cardiol...
  • Cardiologist
  • 25 Years Experience
  • Max Super Speciality Hospital, Saket

Dr. Ripen Gupta is a highly respected cardiologist at Max Hospital in Saket, New Delhi. With over 25 years of experience in interventional cardiology, Dr. Gupta speci...

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Ganesh Kumar Mani
  • Dr. Ganesh Kumar Mani
  • Chairman, Cardiology
  • Cardiologist
  • 45 Years Experience
  • Max Super Speciality Hospital, Saket

Dr. Ganesh Kumar Mani is a distinguished and highly experienced cardiac surgeon at Max Super Speciality Hospital, Saket, New Delhi. Dr. Mani is one of India's mos...

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Rishi Gupta
  • Dr. Rishi Gupta
  • Chairman
  • Interventional Cardiologist
  • 30 Years Experience
  • Accord Superspeciality Hospital

Dr. Rishi Gupta is a renowned name in cardiology and is considered among the best cardiologists in Faridabad, India. He specializes in Angioplasty and coronary A...

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